Paul Turner Stats, News And Video

An ongoing area of research considerations viral ecology, which addresses how viruses interact molecularly within their hosts, between their hosts, and with their surroundings. In specific, Turner and his laboratory members have used both phages and viruses of eukaryotes as laboratory fashions for elucidating evolutionary guidelines of RNA virus emergence. Paul Turner is the Elihu Professor of Ecology and Evolutionary Biology at Yale University, and school member in Microbiology at Yale School of Medicine. He research the evolutionary genetics of viruses, notably bacteriophages that particularly infect bacterial pathogens, and RNA viruses which might be vector-transmitted by mosquitoes.

Professor Turner works with colleagues at VECTOR to check the natural historical past and evolution of pathogenic RNA viruses corresponding to Crimean Congo Hemorrhagic Fever. His non-research work focuses on growth of human and laboratory capacity for diagnostic microbiology in low-useful resource settings. Turner makes a compelling case that viruses are extra biologically successful than mobile life, such as in a 2013 review that he coauthored . The article examines gauges of biological success, together with numerical abundance, environmental tolerance, type biodiversity, reproductive potential, and widespread influence on different organisms.

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Paul Turner describes the elemental biology of viruses, and supplies an introduction to phage therapy, and the way it may be improved by making use of ‘evolution considering. Dr. Paul Turner is Professor of Ecology and Evolutionary Biology at Yale University, and holds an appointment in the Microbiology Program at Yale School of Medicine. His laboratory studies how viruses evolutionarily adapt to overcome environmental challenges, such as temperature adjustments or infection of novel host species. Turner received his bachelor’s degree in Biology from the University of Rochester in 1988, and accomplished his graduate studies in microbial ecology and evolution at Michigan State University in 1995. Turner’s applied analysis consists of looking for natural products that could be useful in combating essential pathogens.

The primary focus of Paul Turner’s analysis is to check the evolutionary genetics and genomics of microbes, particularly the power of viruses to adapt to modifications of their biotic and abiotic environments. These research concern environmental challenges faced by viruses in any respect levels of biological group, together with effects of modifications in molecules, proteins, cells, populations, communities and ecosystems. His work is extremely interdisciplinary, employing microbiology, computational biology, genomics, molecular biology and mathematical-modeling approaches, and particularly experimental evolution (‘evolution-in-motion’) research underneath managed laboratory situations. Turner makes use of a wide variety of RNA and DNA viruses in his research, including varied lytic, temperate and filamentous phages that infect bacteria.

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Conducting interdisciplinary and experimental evolution studies of microbes, Turner and his colleagues elucidate virus evolution and ecology and host–parasite interactions, amongst other subjects. Turner, who was elected to the National Academy of Sciences in 2019, also conducts applied analysis on the event of virus-based mostly therapies that maintain promise for combating antibiotic-resistant bacterial pathogens. His Inaugural Article contributes to that physique of research, which helps to launch a brand new era in phage biotechnology. Turner’s research has led to renewed interest within the medical potential of phages. In a recent evaluate, he and colleagues in contrast phage remedy with chemical antibiotics and highlighted their potential synergies when used in combination . The article emphasizes that the new strategy not solely uses viruses to kill pathogenic micro organism, but in addition selects for increased antibiotic sensitivity within the remaining bacterial inhabitants.

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• Paul Turner is the Elihu Professor of Ecology and Evolutionary Biology at Yale University, and faculty member in Microbiology at Yale School of Medicine.
• He additionally often collaborates together with his graduate college students and postdoctoral fellows, crediting his college students and mentees for their inspiration and help through the years.
• at Imperial College London, the place his sponsors embody John Warner, Stephen Durham and Gideon Lack.

Turner’s research regularly makes use of microbes as mannequin systems to check evolutionary and ecological theories. With Lenski and a colleague, Turner used plasmids as fashions to check the theorized systematic trade-off between infectious and intergenerational modes of parasite transmission . The researchers confirmed that infectious parasites can not evolve to simultaneously maximize horizontal and vertical transfers between hosts.

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